CHROMATOCEL® S-200 Silica Gel for Chromatography & Purification
CHROMATOCEL® S-200 Silica Gel for Chromatography & Purification - 500kg (1102 lbs) Pallet (VENDOR MOQ) is backordered and will ship as soon as it is back in stock.
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Buy 2+ 500kg pallets to save 10%, or 4+ 500kg pallets to save 15% — auto-applied at checkout.
| Minimum Qty | Discount |
|---|---|
| 2 + | 10% off |
| 4 + | 15% off |
CHROMATOCEL® S-200 from Evonik is a high-purity, powdered amorphous silica gel developed for chromatography, batch extraction, decolorization, and purification applications.
Its controlled 70×230 mesh particle distribution is coarser than CHROMATOCEL S-060, supporting more open bed packing and improved flow in compatible chromatography and batch-processing systems. Evonik identifies CHROMATOCEL S-Series silica gels for the separation and purification of small molecules, peptides, lipids, and other compatible compounds.
Product type: Chromatography-grade powdered silica gel
Particle size: 70×230 mesh (approximately 63–200 µm)
Primary uses: Chromatography, batch extraction, decolorization, and purification
Manufacturer: Evonik Operations GmbH
Bulk format: 50 kg (1,103lb) bag
Where it fits
- Large-scale liquid chromatography: Normal-phase separation and purification in compatible production systems.
- Small-molecule purification: Separation and cleanup of compatible organic compounds and intermediates.
- API purification: Process-development and production purification of compatible pharmaceutical ingredients and intermediates.
- Fine-chemical purification: Adsorptive cleanup and fractionation of specialty chemical streams.
- Batch extraction: Adsorptive treatment of compatible liquid-phase process materials.
- Decolorization: Reduction of selected color bodies and polar impurities.
- Peptide and lipid separation: Evaluation as a normal-phase adsorbent where silica chemistry fits the target process.
- Botanical and nutraceutical processing: Purification and fractionation of compatible extracts, subject to process qualification.
Why choose CHROMATOCEL S-200?
- Chromatography-grade silica gel developed specifically for separation and purification work.
- Coarser particle distribution than S-060 for more open packing and potentially lower pressure drop.
- Normal-phase silica chemistry for compatible chromatography, adsorption, and decolorization processes.
- Suitable for scale-up from process development through production-volume requirements.
- Manufacturer-supported applications include large-scale chromatography, small-molecule purification, API purification, and fine-chemical purification.
- Industrial bulk packaging available for recurring plant-scale use.
Typical product information
| Product name | CHROMATOCEL® S-200 |
|---|---|
| Product type | Silica gel / chromatography grade |
| Chemical name | Silica gel; silicon dioxide |
| CAS number | 112926-00-8 |
| Physical form | Powdered amorphous silica gel |
| Particle size | 70×230 mesh (approximately 63–200 µm) |
| Separation mode | Normal-phase adsorption and chromatography |
| Manufacturer | Evonik Operations GmbH |
| Bulk packaging | 500kg (1,103lb) bag |
The current Evonik S-200 Technical Data Sheet should be reviewed for detailed physical-property limits and qualification requirements. Do not treat unverified historical or representative values as guaranteed specifications.
CHROMATOCEL S-200 vs. S-060
| Selection factor | CHROMATOCEL S-200 | CHROMATOCEL S-060 |
|---|---|---|
| Particle size | 70×230 mesh, approximately 63–200 µm | 230×400 mesh, approximately 37–63 µm |
| Relative particle size | Coarser | Finer |
| Flow characteristics | Generally more open packing and lower resistance under comparable conditions | Generally tighter packing and greater flow resistance under comparable conditions |
| Surface contact | Larger particles provide less external surface contact per unit mass | Finer particles provide greater external contact and potentially tighter separation |
| Typical starting point | Processes prioritizing flow, throughput, and easier handling | Processes prioritizing finer separation and increased adsorbent contact |
Actual separation, pressure drop, recovery, and throughput depend on bed geometry, packing, solvent composition, viscosity, loading rate, and target compounds. Grade selection should be confirmed through testing.
Application and trial guidance
- Evaluate the silica using the actual feed material, mobile phase or solvent system, target compounds, and impurity profile.
- For chromatography, establish packing method, bed depth, flow rate, sample loading, elution conditions, and fraction criteria experimentally.
- For batch treatment, optimize silica dosage, mixing, contact time, temperature, and downstream filtration.
- Monitor product recovery and yield in addition to impurity removal or color reduction.
- Confirm that the coarser particle distribution provides acceptable separation efficiency at the desired throughput.
- Use suitable downstream filtration to prevent silica particles from remaining in the finished material.
- Complete process-specific qualification before using the product in regulated or specification-sensitive applications.
Qualification note: Evonik states that product performance should be verified through testing conducted by qualified personnel. Application descriptions do not replace customer validation using the actual process.
Packaging & availability
| Manufacturer package | Published configuration |
|---|---|
| Bag | 28lb (12.7kg) |
| Small drum | 30lb (13.6kg) |
| Large drum | 60lb (27.2kg) |
| Bulk bag | 1,103lb (500kg) |
- Sorbents Direct listing: 500kg bulk-bag quantities.
- Minimum order: 500kg (1,103lb bulk bag).
- Lead time: Typically 2-4 weeks, subject to inventory, quantity, shipping point, and destination.
- Freight: Calculated or quoted based on pallet count, shipment weight, and delivery requirements.
- Volume pricing: Automatic quantity discounts may be available for qualifying bulk-bag orders.
Volume discounts
- 2+ units / 1,000 kg or more: 10% automatic quantity discount.
- 4+ units / 2,000 kg or more: 15% automatic quantity discount.
Current prices and discounts are displayed on the product listing and should be confirmed before purchase.
Storage and shelf life
- Store in the original packaging in a dry, covered location.
- Keep bags and drums tightly sealed until use.
- Reseal partially used containers promptly to minimize atmospheric moisture adsorption.
- Protect the silica from liquid water, rain, direct sunlight, oils, solvents, dust, and foreign contamination.
- Keep packaged material elevated from the ground in a protected storage area.
- Use clean, dry handling and transfer equipment.
Published shelf life: Three years in the original packaging when stored in a dry, covered location.
Handling considerations
- Avoid generating or breathing airborne silica dust.
- Use appropriate local exhaust ventilation during bulk-bag discharge, transfer, charging, and cleanup.
- Wear eye protection and other personal protective equipment specified by the current Evonik SDS and site risk assessment.
- Use suitable industrial vacuum equipment or low-dust cleanup methods rather than dispersing powder with compressed air.
- Handle spent silica according to the hazards and properties of the substances it has adsorbed.
Important: Request and review the current Evonik Safety Data Sheet before handling. A technical product-information sheet does not replace an SDS.
Why buy from Sorbents Direct?
Sorbents Direct helps industrial buyers evaluate silica grade, particle size, order quantity, documentation, and freight requirements before purchase.
- Industrial bulk quantities for production-scale chromatography and purification.
- Current manufacturer documentation available for technical review and qualification.
- Lot-specific COA support when available for shipped material.
- Grade-selection assistance when comparing S-200 with finer S-060 silica.
- Transparent volume pricing for qualifying bulk orders.
- Freight and delivery support for pallet and bulk-bag shipments.
Documentation & technical support
Evonik provides a Technical Data Sheet and Safety Data Sheet for CHROMATOCEL S-200. The current TDS is available through Evonik’s authenticated product portal, and a lot-specific Certificate of Analysis may be requested for shipped material.
Visit our Documentation Center or contact Sorbents Direct to discuss your feed material, separation objective, solvent system, process scale, annual volume, and documentation requirements.
Questions & answers
What is CHROMATOCEL S-200?
CHROMATOCEL S-200 is a powdered, chromatography-grade silica gel manufactured by Evonik for liquid chromatography, batch extraction, decolorization, and purification.
What is the particle size?
CHROMATOCEL S-200 uses a 70×230 mesh particle distribution, corresponding approximately to 63–200 microns.
How does S-200 compare with S-060?
S-200 is the coarser grade at approximately 63–200 microns. S-060 is finer at approximately 37–63 microns. S-200 is generally considered where more open flow is desired, while S-060 may be preferred where finer contact and tighter separation are priorities.
What applications does Evonik list?
Evonik lists large-scale liquid chromatography, small-molecule purification, API purification, and fine-chemical purification as typical applications.
Can it be used for batch extraction and decolorization?
Yes. Evonik specifically describes CHROMATOCEL S-200 as a powdered silica gel for chromatography, batch extraction, and decolorization.
What is the minimum order?
The current Sorbents Direct minimum is 500kg.
What package sizes does Evonik publish?
Evonik publishes 12.7 kg bags, 13.6 kg drums, 27.2 kg drums, and 500 kg bulk bags. The Sorbents Direct listing currently focuses on 500 kg bulk bags.
What is the typical lead time?
Typical lead time is approximately 2–4 weeks, subject to inventory, order quantity, package format, and destination.
What is the shelf life?
Evonik publishes a three-year shelf life in the original packaging when stored in a dry, covered location.
Why are detailed physical-property ranges not shown here?
The current detailed S-200 Technical Data Sheet is provided through Evonik’s authenticated product portal. Exact property limits should be taken from that current document rather than unverified representative values.
What documentation is available?
Evonik provides a Technical Data Sheet and Safety Data Sheet. A lot-specific Certificate of Analysis may also be requested for shipped material.
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CHROMATOCEL® S-200 Silica Gel for Chromatography & Purification
